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RECOGNITION AND MANAGEMENT OF OSTEOARTHRITIS PAIN IN ANIMALS

By Dr. David J. DeQuick, DVM

 

Thanks to advanced medical care, technology, and pets’ changing status as members of the family, companion animals are leading longer lives.  Unfortunately, the growing senior pet population means more animals suffer from chronic pain.  This pain can be derived from neoplasia, neurologic conditions, myopathies, or chronic inflammatory conditions, especially, osteoarthritis (OA), which is the leading cause of chronic pain in pets.

 

Severe hip dysplasia ans osteo-arthritisVariable responses among species to pain and distress make recognition of the problem difficult.  Pain is considered to be universally protective in nature and part of the flight and fright mechanism.  Unfortunately, pets can’t tell their owner where they hurt or tell if the problem corresponds to pain or is one of anxiety or fear.  If you see signs of discomfort, stiffness and lameness, your pet is probably in pain.  Dogs display a wide variety of responses to pain.  They may be violent and vocalize or quiet, withdrawn and inactive.  They may be aggressive when approached, as they try to protect themselves from further pain, or they may be subdued or withdrawn.  They may lick at the affected area or even lay their ears flat against their head.

 

A key to recognizing pain is present in your pet is to look for a change of behavior.  Osteoarthritis (OA) is a chronic condition that progressively manifests itself over time.  Pain, stiffness and lameness increase as the condition worsens.  Behavioral changes such as decreased activity, reluctance to run, jump, climb stairs or play, limping, difficulty rising, sitting or squatting to eliminate, lagging behind on walks, soreness when touched, yelping or whimpering, loss of appetite and acting aggressive or withdrawn are classic signs of worsening OA.  Since signs of pain are often subtle and can be confused with a perception of “old age”, it requires astute observation of your pet to pick up on these changes.
 

Approximately, 20% of all adult dogs suffer with progressive OA.  Controlling chronic pain involves pharmacologic, physical, environmental, and behavioral management.  Providing pain relief via drug therapy is an important means of control.  Environmental and behavioral management are important adjuncts to drug therapy.  Appropriate patient care includes a comfortable ambient temperature and level of humidity, adequate bedding, satisfactory rest and sleep, compassionate care, and owner visitation provides psychological well-being of the patient, thus enabling the patient to tolerate its painful state better.

 Dogs

There is no cure for OA.  It is a chronic disease that requires continuous treatment but early detection and careful management can reduce your pet’s pain and improve his quality of life.  Pain relief drugs include steroidal and non-steroidal (NSAID’s) compounds.  Because of potential harmful side-effects of regular usage of steroidal drugs, NSAID’s are commonly prescribed, specifically, Rimadyl and Deramaxx.  These products are found to relieve pain by inhibiting the production of an enzyme called COX-2, thereby blocking a process that creates prostaglandins, the enzymes that are associated with pain and inflammation.

 

Additional pain relief therapy can be achieved by providing nutritional supplementation to the intricate components of the inner aspects of the joints.  The joint capsule absorbs the shock of impact of motion and cartilage prevents the ends of the bones from damaging each other while in motion.  The inner synovial membrane shields the joint and contains the synovial fluid, which lubricates and nourishes the joint and forms a barrier to inflammatory cells.  Joints rely on healthy synovial fluid to transport the vital nutrients needed by cartilage and other connective tissues.  As articular cartilage becomes damaged it has considerable difficulty in repairing itself because it does not receive blood circulation and must rely on the weakened synovial fluid for nourishment.  As articular cartilage degeneration progresses, it exposes the bone to friction during movement, which causes inflammation and then pain which leads to decreased mobility.  Glucosamine and Glycosaminoglycans (GAGs) like Perna Canaliculus and Sea Algae are nutraceutical (natural NSAID supplement) products which stimulate synovial fluid synthesis and replenish the essential building blocks necessary to maintain a healthy cartilage matrix which aids in preventing joint degradation.

 

GAGs are chondroprotective agents that help rebuild damaged connective tissues and provide lubricating properties to the synovial fluid.  Glucosamine is an integral part of the “glue” that holds tissue cells together and is necessary for production of key tissue components that rejuvenate and maintain articular cartilage.  Methylsulfonylmethane (MSM) is a natural dietary sulfur compound which helps to lessen pain associated with inflammation and is added to supplements which are manufactured for preventative care supplements which enhance joint health, strength, energy and mobility.  Creatine Monohydrate, Omega-3 Fatty Acids, Antioxidants (Vitamin E, Lipoic Acid and Grape Seed Extract), Vitamins and Minerals are also added to these products to help strengthen muscles and tendons and further enhance anti-inflammatory action.

 

Current therapy for OA has progressed significantly through the past several years which have helped to extend our beloved pets lives and provide profound pain relief.  Reversing the degeneration of the inner joint components and stimulating repair processes provides a better opportunity for the joint to return to normal.  This is achieved via a multiplicity of medications as well as weight loss, controlled exercise, nutraceuticals, diet and adjunct therapy such as acupuncture and chiropractic adjustments to achieve optimal results.  This enables our four-legged family members to maintain mobility which leads to more play and tail-wagging even in their senior years.


   
 

 

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